Search results for "Dose calculation"

EP-1186: Accuracy of the TG-43 dose calculation formalism for HDR skin brachytherapy

2013

Monte Carlo calculation of the TG-43 dosimetric parameters of a new BEBIG Ir-192 HDR source

2005

Background and purpose: High dose rate (HDR) brachytherapy is a highly extended practice in clinical brachytherapy today. Quality dose rate distribution datasets of the HDR sources used in a clinical treatment are required. Because of the different source designs, a specific dosimetry dataset is required for each source model. In the recently published BRAPHYQS-ESTRO Report, an overview of available dosimetric data for all HDR Ir-192 sources is given, pointing out the lack of data for one of the sources that is used by the BEBIG MultiSource afterloading system (BEBIG GmbH, Germany). The purpose of this study is to obtain detailed dose rate distributions in liquid water media around this sou…

A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy

2017

PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-19…

Model-Based Dose Calculation Algorithms for Brachytherapy Dosimetry

2019

The purpose of this study was to review the limitations of dose calculation formalisms for photon-emitting brachytherapy sources based on the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) report and to provide recommendations to transition to model-based dose calculation algorithms. Additionally, an overview of these algorithms and approaches is presented. The influence of tissue and seed/applicator heterogeneities on brachytherapy dose distributions for breast, gynecologic, head and neck, rectum, and prostate cancers as well as eye plaques and electronic brachytherapy treatments were investigated by comparing dose calculations based on the TG-43 formalism …

Limitations of the TG-43 formalism for skin high-dose-rate brachytherapy dose calculations

2014

Purpose: In skin high-dose-rate (HDR) brachytherapy, sources are located outside, in contact with, or implanted at some depth below the skin surface. Most treatment planning systems use the TG-43 formalism, which is based on single-source dose superposition within an infinite water medium without accounting for the true geometry in which conditions for scattered radiation are altered by the presence of air. The purpose of this study is to evaluate the dosimetric limitations of the TG-43 formalism in HDR skin brachytherapy and the potential clinical impact. Methods: Dose rate distributions of typical configurations used in skin brachytherapy were obtained: a 5 cm × 5 cm superficial mould; a …

Implementation and Validation of an End-to-End Commissioning Process for Model-Based Dose Calculation Algorithms in Brachytherapy

2016

TU-E-116-01: Clinical Implementation for Advanced Brachytherapy Dose Calculation Algorithms Beyond the TG-43 Formalism

2013

With the recent introduction of heterogeneity correction algorithms for brachytherapy, the AAPM community is still unclear on how to commission and implement these into clinical practice. The recently‐published AAPM TG‐186 report discusses important issues for clinical implementation of these algorithms. In this practical medical physics course, specific examples on how to perform the commissioning process are presented, as well as descriptions of the clinical impact from recent literature reporting comparisons of TG‐43 and heterogeneity‐based dosimetry. A proposed commissioning flowchart will be discussed, guiding the audience through the clinical process. Further, QA tests specific to the…

Body composition characteristics and body surface area

2013

Chemotherapy dose calculation for oncologycal patient is using the human body surface area (BSA). BSA is a variable with a difficult constitutional body and physiological assessment. BSA does not reflect the exercise on body composition in relation to the various body modifications: obesity, amputation of body parts, pregnancy. Body surface area despite the documented limitations remains the most commonly used parameter chemotherapy (cytotoxic therapy) of cancer patients. The new guidelines are intended obese patients is to achieve the same maximum dose rate calculated BSA taking into account the full weight rather than using the statement or reduce weight by restricting intake. Experience …

A Generic High-Dose-Rate 192Ir Source Model for Model-Based Dose Calculation Methods in Brachytherapy Beyond the TG-43 Formalism

2013

SU-FF-T-13: Monte Carlo Calculation of the TG-43 Dosimetric Parameters of a New BEBIG Ir-192 HDR Source

2005

Purpose: High dose rate (HDR) brachytherapy is a highly extended practice in clinical brachytherapy today. Quality dose rate distribution datasets of the HDR sources used in a clinical treatment are required. Because of the different source designs, a specific dosimetry dataset is required for each source model. In the recently published BRAPHYQS-ESTRO Report, an overview of available dosimetric data for all HDR Ir-192 sources is given, pointing out the lack of data for one of the sources, the used by the BEBIG MultiSource afterloading system (BEBIG GmbH, Germany). The purpose of this study is to obtain detailed dose rate distributions in liquid water media around this source. Material and …